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AncestryDNA's service is particularly well suited for leveraging an introductory DNA analysis into deep historical research to build out a family tree. The basic DNA kit service provides you with an "ethnicity estimate" derived from its proprietary sequencing techniques. It's noteworthy that the company's genetic testing, which is outsourced to Quest Diagnostics, is distinct from that of most other companies, which use paternal Y chromosome and/or maternal mitochondrial DNA methodologies, and less is known about the particular criteria it uses.
AncestryDNA says its database contains more than 18 million profiles, making it the largest of all the DNA test kit services. The company also maintains a powerful tool for searching through hundreds of historical document databases, but any substantive research will quickly bring you to a paywall.
An entry-level membership provides access to more than 6 billion records in the US and includes a free two-week trial. The World Explorer membership broadens your access to the company's 27 billion international records. The All Access tier includes unlimited access to Ancestry's historical and contemporary database of more than 15,000 newspapers and military records from around the world.
FamilyTreeDNA offers all three types of DNA tests: autosomal DNA, Y-DNA and mtDNA. It's the sole company to own and operate its own testing facility, The Houston-based Gene-by-Gene genetic lab.
The user interface is a bit more complicated than what you'll find on other sites, but FamilyTreeDNA provides the most complete suite of introductory tools of any provider we tested. For each type of test, you're presented with matches, a chromosome browser, migration maps, haplogroups and connections to ancestral reference populations, information about mutations and a link that lets you download your raw data.
The company's entry-level Family Finder package costs $79. The test results provide information about your ethnic and geographic origins, identify potential relatives and offer access to the company's massive DNA database. There is also a Maternal Ancestry test for $159, Paternal Ancestry for $199 and a Paternal Ancestry in Great Detail package for $449.
The three services above are our top choices for the best DNA test. They weren't the only ones we tested. What follows are some additional options, none of which eclipsed the 23andMe, Ancestry or FamilyTreeDNA in any significant fashion.
MyHeritage offers a free tier of service that includes some basic family tree-building and access to excerpts of historical documents. It also includes a report of your genetic makeup across the company's 42 supported ethnicities, the identification of relatives and connections to them where possible.
We found MyHeritage's user interface far less intuitive and more difficult to navigate than others. It's one of the few companies to offer a comprehensive research database of historical documents, DNA analysis and health screening, but we found the integration among them to be a bit clumsy. In 2018, MyHeritage committed a security breach, exposing the email addresses and hashed passwords of more than 92 million users.
LivingDNA divides its offerings in a different way than others. Your Ancestry DNA kit provides an overview of your ancestry in 150 geographical regions and information about maternal and paternal haplogroups and access to the company's genetic matching tool. The $109 "well-being package" includes reports about your physiological compatibility with vitamins, foods and exercise. The $169 Wellbeing and Ancestry gives you all of it.
Despite not selling or sharing data, the company has a very limited family match database; a company representative declined to give me a specific number but said that it contained less than 1 million profiles. If you're looking to identify and make connections with relatives, there are better choices in the market.
There are multiple companies, including Full Genomes, Veritas Genetics, Nebula Genomics and Dante Labs, that can sequence all of your DNA -- otherwise known as your genome. This level of analysis is appropriate for advanced users only. Not only is it expensive -- these tests can run into the thousands of dollars, in some cases -- it requires a sophisticated understanding of both genetics and a range of technical tools required to explore and interpret your results. The least expensive whole genome tests cost about $250.
For most people, the main rationale for sequencing the whole genome is to dive deep into your genetic health outlook. You can glean your personal risk factors for diseases, drug sensitivities and your status as a carrier; that is, what you might pass on to your kids. All of these efforts can also be undertaken (to a less intense degree) with some of the more affordable options outlined above. We suggest starting with Nebula Genomics. You can also upload an existing DNA sequence from Ancestry or 23andMe's DNA database and get Nebula's reports at a reduced price.
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HomeDNA sells testing kits under several brands, including DNA Origins, and has a retail presence at Walmart, CVS, Rite Aid and Walgreens. This company doesn't have a sterling reputation in the genetic genealogy world. When we recently spoke with Debbie Kennett, a genetic genealogist from University College London, she referenced the company's notoriety for delivering "bizarre results" and expressed doubt about the efficacy of its specialized tests for particular ethnic groups. HomeDNA did not respond to CNET's inquiry about its testing process or results.
HomeDNA reports don't stack up particularly well against those returned by other companies. Results are summarized on a single webpage, although you also get a PDF that certifies that you've "undergone DNA testing" and shows the continents and countries where your DNA originates. There's no obvious next step or any actionable data that comes with your results.
African Ancestry promises to trace its customers' ancestry back to a specific country and identify their "ethnic group origin." Unlike most other companies, African Ancestry doesn't offer an autosomal DNA test. Instead, it offers an mtDNA test or a Y-DNA test (for males only). In contrast to your standard DNA analysis, African Ancestry's report doesn't provide the percentage of DNA that's likely to have originated across a range of regions. Instead, African Ancestry claims to trace your DNA to a specific region of Africa.
According to experts, African Ancestry's DNA tests come up short. As explained in a blog post by African American genetic genealogist Shannon Christmas, the company's methodology simply doesn't analyze a sufficient number of DNA markers to deliver on its marketing promises.
On the plus side, African Ancestry says that it does not maintain a database of customer information and that it will not share or sell your DNA sequence or markers with any third party, including law enforcement agencies. African Ancestry promises to destroy your DNA sample after your test results are delivered.
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We did a lot of research into the DNA testing market, addressing each option based on its price, database size and the depth of its offerings. We also noted their methodologies and reputation. We also noted additional factors such as family matching and privacy policies.
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There are many options for home DNA tests out there, not all of which are the right choice for you. When shopping, you should keep a few key factors in mind that'll help you find the best DNA test for you.
To start, you need to decide what your goal is when it comes to testing your DNA. Are you trying to connect with family members, explore historical documents or get a snapshot of your health traits? While many of the best DNA tests overlap in what they offer, most shine in particular areas. For example, Ancestry is the best DNA test choice if you want to use your DNA analysis to dive into historical research to build your family tree.
DNA tests aren't what I'd consider cheap, although affordable options exist. It's essential to keep your budget in mind when shopping for a DNA test. Some tests have tiered offerings at a flat rate, while others require subscription fees to access their databases.
Volunteering your health information to companies is a big deal. Before you buy, you should fully understand what happens to your data and results. It's shared with you, but who else has access to it? Some DNA testing companies share your results with law enforcement and pharmaceutical companies.
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If you're using a home DNA testing service, you're likely looking for one of three things:
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Afraid of needles and drawing blood? Good news: That's not an issue with the best DNA tests. All you need to do is spit into a vial or rub a swab in your mouth -- all the genetic data needed for these tests is present in your saliva -- and ship the DNA sample to the company for analysis.
The reason that a saliva sample works, as well as blood (or hair follicles or skin samples), is that your DNA -- which is short for deoxyribonucleic acid -- is present in all of them. It's the basic genetic code present in all of your cells that makes up your key attributes, from the color of your eyes to the shape of your ears to how susceptible you are to cholesterol.
The key terms you need to know when comparing DNA testing services are:
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There are three types of DNA tests, each with its own particular strengths, limitations and rationales.
Each testing company will give you an analysis of your DNA test results. These results could include your geographical origin -- some claim to be able to pinpoint a specific country, town or even "tribe" -- as well as your genetic ancestry composition and your susceptibility to particular genetic diseases. We should note that these tests don't serve a diagnostic purpose. A doctor-administered genetic test and a follow-up with a genetic counselor are important if you think you have a genetic disease. No online testing company offering results from a saliva sample can substitute for a health test administered by your doctor.
Certain companies will also serve up "matches" from their DNA databases, which will give you a head start on connecting with possible relatives and offer some degree of family-tree research support. AncestryDNA, for example, offers a subscription service that includes access to hundreds of databases containing birth, death and marriage announcements, census documents, newspaper archives and other historical records.
Some DNA companies sell tests designed for specific ethnicities or specialized kits that claim to shed light on your optimal skin care regimen or weight; others offer tests designed to identify the genetic makeup of your cat or dog. (Yes, you can get a dog DNA test.) The experts we spoke to were dubious of the efficacy and value of these tests and recommended avoiding them.
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Yes, DNA tests are the most accurate way to determine the paternity of a child. Samples need to be collected from both the child and the suspected parent to make a determination. For the best accuracy, you need a test that specifically checks for paternity not just ancestry.
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Yes. Several companies sell dog DNA tests to help you determine the breed of your animal and screen for possible genetic health issues.
Three popular brands are Wisdom Panel (for both dogs and cats), Embark (for dogs only), and Basepaws (for cats only).
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David Gewirtz contributed to this story. The current version is a major update of past revisions and includes hands-on impressions of most of the services listed.
Source: cnet.com