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Glucose-to-Potassium Ratio Predicts Kidney Injury After Brain Trauma

A large study identifies a specific glucose-to-potassium ratio threshold as an early warning sign for acute kidney injury following traumatic brain injury.

2026-06-30T15:00:59.263Z

Glucose-to-Potassium Ratio Predicts Kidney Injury After Brain Trauma

A new study reveals the glucose-to-potassium ratio, or GPR, is a key predictor of acute kidney injury in patients with traumatic brain injury.

The analysis of nearly 2,400 patients found a non-linear, J-shaped relationship. Kidney injury risk increases sharply once the GPR exceeds a value of 30.

This pattern suggests elevated GPR may signal metabolic stress after a brain injury. A predictive model using this ratio outperformed traditional methods.

Clinicians could use this marker for early risk identification. The findings support closer monitoring of brain injury patients with a high GPR on admission.

Topics Glucose-to-Potassium Ratio AKI Traumatic Brain Injury MIMIC-IV Sci Rep