A deep diagonal line in the earlobe could be more than a wrinkle-it may be a warning sign of heart disease. Known as Frank’s sign, this feature was first linked to coronary artery disease by Dr. Sanders T. Frank in the 1970s.

The crease runs from the tragus at a 45-degree angle to the outer edge of the lobe. It can appear on one or both ears, with bilateral creases showing a stronger association with cardiovascular issues.

Researchers believe the link may lie in shared blood supply patterns or the breakdown of elastic fibers. Earlobes and heart arteries rely on end arteries-vessels without backup circulation. Compromised blood flow could damage both tissues.

While aging increases both wrinkles and heart disease risk, studies show Frank’s sign remains an independent predictor even after adjusting for age, smoking, and diabetes.

A true Frank’s sign is permanent. Temporary sleep creases fade quickly. If you notice the line, don’t panic-but do mention it at your next checkup. It’s one clue among many in assessing heart health.