hepatocytes
2 stories
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healthMIT’s Injectable ‘Satellite Livers’ Show 2-Month Viability in Mice, Offering Hope for Patients Beyond Transplant Lists
MIT researchers developed injectable hydrogel-encased hepatocytes that functioned as mini-livers in mice, surviving two months. The technology could provide a bridge or alternative to organ transplantation for chronic liver failure patients, especially those too frail for surgery.
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healthEpigenetic Silencing Undermines Longevity of AAV Gene Therapy
New research reveals epigenetic mechanisms reduce durability of AAV gene therapy in liver cells, challenging long-term efficacy for hemophilia treatment.