Americans born after 1970 are dying at significantly higher rates in middle age than their predecessors, marking a stark reversal in decades of improving life expectancy. New analysis from Tufts University, published in the Proceedings of the National Academy of Sciences, tracks 45 years of mortality data from 1979 to 2019.

While those born in the 1940s saw steady survival improvements, progress slowed for the 1950s cohort and reversed for Gen X and Millennials. Between ages 30 and 49, post-1970 Americans face elevated death rates from heart disease, cancer, and external causes including drug overdoses, suicide, and accidents.

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Researchers identify two primary drivers: generational decline, where newer cohorts enter middle age with higher risk factors like obesity and diabetes; and a nationwide setback beginning around 2010 that stalled cardiovascular progress. The opioid epidemic and widening economic inequality further exacerbate these trends.

U.S. life expectancy gains dropped to just 0.26 years between 2010 and 2019, compared to an average of 1.78 years per decade previously. This has widened the gap between the U.S. and top-performing nations. Lead author Leah Abrams suggests interventions targeting hypertension, obesity, and diet could mitigate rising colon cancer and cardiovascular mortality.

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