Kidney transplant recipients (KTRs) face an elevated risk of HPV-related cancers due to long-term immunosuppression therapy, with cervical cancer incidence rates significantly higher than the general population.

A new single-center study from Ireland assessed current adherence to prevention strategies. For cervical screening, 87% of surveyed female KTRs under 65 had attended a screening appointment since transplantation, and all cited prompt attendance following national program reminders. However, nearly half of the participants had required a colposcopy following an abnormal test result.

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Conversely, HPV vaccination rates remain critically low. Only 22% of eligible recipients had received the vaccine. While 87% of the cohort acknowledged their elevated lifetime cancer risk, only 9% were aware that the HPV vaccine could mitigate this specific danger. Critically, all unvaccinated patients stated they would accept the immunization if provided directly by their hospital’s renal department.

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Researchers advocate integrating the HPV vaccine into established hospital workflows, mirroring the long-standing, cost-effective delivery model used for Hepatitis B vaccinations in renal units, as a vital quality improvement initiative to close this preventable gap in care.