An international team has identified a significant health marker. A large analysis of over 26,000 men reveals a strong association between very low testosterone levels and a higher risk of dying from cancer.
The research, published in The Lancet Healthy Longevity, found that men in the lowest one-fifth for testosterone concentration faced elevated mortality risk, even after accounting for age and other factors. Cancer risk began to increase when levels fell below 8.6 nanomoles per liter.
"Low testosterone is an important biomarker," says endocrinologist Bu Yeap of The University of Western Australia. "It's possible that looking at testosterone levels could help us identify men who might do poorly if they get cancer."
A key exception is prostate cancer. The study found no evidence linking a man's naturally produced testosterone to prostate cancer risk, a somewhat surprising finding given the organ's responsiveness to the hormone.
Researchers stress this is a correlation, not a proven cause. They caution against using testosterone supplements as a preventive measure. Instead, a low reading should prompt a comprehensive medical check-up to address other potential health issues.
The findings suggest hormonal levels could serve as a wake-up call, encouraging healthier lifestyles and regular, holistic health monitoring.