A large retrospective study spanning 13 years and 371 mastectomies shows that minimally invasive endoscopic and robotic techniques deliver broadly comparable surgical and patient-reported outcomes in single-incision nipple-sparing mastectomy.

Both incision approaches-axillary crease and lateral chest wall-produced similar rates of post-operative complications, oncological safety, and patient satisfaction. Nipple preservation, margin involvement, and sensory outcomes were also equivalent.

Small technical differences appeared: In endoscopic procedures, lateral chest wall incision reduced operative time, but this advantage wasn't seen in robotic-assisted surgeries. Delayed wound healing occurred more often with lateral chest wall incision, possibly due to increased skin tension.

Patient satisfaction with breast appearance, scar position, and well-being was high in both groups, with most patients saying they would choose the same procedure again.

Researchers conclude that incision choice should be guided by surgical approach and anatomical factors rather than effectiveness or satisfaction.