Edmonton researchers have launched a pivotal clinical trial aimed at treating trigeminal neuralgia, historically termed the "suicide disease" due to its excruciating intensity.

Dr. Tejas Sankar, a neurosurgeon at the University of Alberta Hospital, emphasizes that this condition causes some of the most severe pain known to mankind. Historically, medication management failed many patients due to side effects or limited efficacy.

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The new protocol introduces "ultra-early" Gamma Knife surgery as a first-line treatment rather than a last resort. Researchers aim to intervene immediately after diagnosis to halt structural changes in the brain.

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The University of Alberta Hospital’s Scott and Brown Families Gamma Knife Centre is recruiting 80 patients across the province. Half will receive standard care, while the other half undergoes immediate radiation therapy.

Success stories suggest the procedure renders patients pain-free and off medications within months. The trial aims to prove that early intervention prevents chronic pain from becoming permanent.