England's quest for an eighth consecutive Women's Six Nations title has been hampered by further injuries. Hannah Botterman and May Campbell have been ruled out for the remainder of the tournament due to injuries requiring surgery.
Lock Delaney Burns and prop Liz Crake have been called up as replacements. Botterman is undergoing a second operation on an ankle injury, while Campbell will have surgery on a knee injury next week.
This adds to existing absences, including Morwenna Talling and Natasha Hunt, and pregnancies affecting Zoe Stratford, Abbie Ward, and Rosie Galligan. England is currently level on points with France heading into their match against Scotland.