Italy coach Gonzalo Quesada has made three key alterations to the starting lineup for Saturday's final Six Nations fixture against Wales in Cardiff. Muhamed Hasa will step in at prop to replace the injured Simone Ferrari, who sustained a neck injury during Italy's historic victory over England last weekend. Hasa's inclusion marks his first Six Nations start.

Alessandro Fusco returns at scrumhalf, taking over from Alessandro Garbisi, while Federico Ruzza is preferred at lock over Andrea Zambonin. Stephen Varney is set to make his first appearance of the tournament on the replacements' bench.

Italy enters the match with momentum, having secured their first-ever win against England, following an earlier victory over Scotland. A win against Wales would secure their best Six Nations performance since joining the competition in 2000.

Wales, currently at the bottom of the standings without a win, are looking to end a 15-game losing streak in the tournament. They have lost their last two Six Nations encounters against Italy.