TGF-β
2 stories
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healthTREM2 Feedback Loop Drives Liver Fibrosis: Study Reveals Therapeutic Target
Scientists identify a self-reinforcing TREM2/LDHA pathway in scar-associated macrophages that drives liver scarring, offering a potential anti-fibrotic treatment strategy.
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healthProton Pump Inhibitors Show Antifibrotic Power in Eosinophilic Esophagitis
New research reveals proton pump inhibitors (PPIs) can directly reduce esophageal fibrosis and remodeling in eosinophilic esophagitis (EoE), suggesting disease-modifying potential beyond anti-inflammatory effects.