New research indicates that e-cigarette use in young adults, aged 18-25, is associated with a significantly higher risk of early cognitive decline.

The study analyzed 232 participants in Thailand, comparing e-cigarette users with non-smokers.

While no significant differences were found in ADHD symptoms or emotional intelligence, e-cigarette users showed a markedly higher proportion at risk of dementia. Those with no intention to quit within six months faced a fourfold increased risk.

These findings suggest potential neurocognitive changes emerging in early adulthood, although dementia risk was inferred from screening scores, not clinical diagnosis.

The study’s cross-sectional design limits causal interpretation, but the results highlight public health concerns given the global rise in e-cigarette use among younger populations.

Further longitudinal research is needed to clarify causality and explore potential mitigation through reduced or discontinued e-cigarette use.