A major study analyzing over 350,000 participants from the UK Biobank has found a strong link between coffee consumption and reduced liver disease risk.
Researchers tracked participants for 13 years. Those drinking five or more cups daily showed a 32% lower risk of cirrhosis, a 47% lower chance of liver cancer, and a 42% reduction in liver-related deaths.
The benefits extended to liver health markers. Coffee drinkers had lower levels of liver fat, iron, fibrosis, and inflammation. Their blood tests showed proteins linked to healthy function and lower levels of those tied to scarring.
The study, published in Clinical Gastroenterology and Hepatology, noted both caffeinated and decaffeinated coffee showed similar associations. The strongest effect was seen at three to four cups per day, but even one to two cups provided significant protection.
Lead author Ju Dong Yang stated the findings support moderate coffee consumption for those who tolerate it, but cautioned against starting solely for liver protection.
Experts note high caffeine intake can cause side effects. The generally safe limit for most adults is about 400 milligrams of caffeine daily, roughly four cups of coffee.