A major systematic review and meta-analysis reveals that depression is highly prevalent among women with cervical cancer worldwide, affecting more than one in three patients. Researchers, who analyzed data from nearly 24,000 participants across 20 studies, call for the integration of routine mental health screening into cervical cancer care.
The pooled prevalence of depression stood at 38.02%. Rates were significantly higher in Africa, at 52.51%, and in studies conducted after 2020, at 49.15%. In contrast, European studies reported a lower prevalence of 12.26%. The study also found that cross-sectional designs yielded higher depression rates compared to other methods.
Cervical cancer is the fourth most common cancer in women globally. Although largely preventable through HPV vaccination and regular screening, the disease remains a significant health challenge. The American Cancer Society notes that one in four people who have or have had cancer experience depression, often starting soon after diagnosis or persisting months after treatment.
Researchers urge healthcare providers to incorporate systematic depression screening and mental health services into cervical cancer management protocols, especially in resource-limited settings. They also recommend comprehensive psychological support programs and enhanced social support mechanisms for patients.