What's good for your aging gut may also be good for your aging brain. A first-of-its-kind study in twins found that taking daily protein and prebiotic supplements can improve memory test scores in people over age 60.
Published in 2024, the findings suggest that inexpensive plant-fiber prebiotics, such as inulin and fructooligosaccharide (FOS), may enhance brain health. The double-blind trial tested these supplements in 36 pairs of twins, all at least 60 years old.
Each duo was randomly split: one twin received a daily prebiotic mixed into protein powder, while the other received a placebo. The twins who unknowingly took inulin or FOS generally scored higher on a cognitive test three months later.
The study also found that the supplements were linked to subtle changes in the gut microbiome, with beneficial bacteria like Bifidobacterium increasing in those taking the prebiotics.
Researchers at King's College London said the results hold promise for enhancing brain health in an aging population. 'We are excited to see these changes in just 12 weeks,' said Mary Ni Lochlainn, a geriatric medicine researcher at KCL.
The findings add to growing evidence that the gut-brain axis plays a critical role in cognitive function. While the study did not show physical benefits like muscle preservation, it highlights the potential of dietary interventions in supporting brain health.
