Researchers at the University of Aveiro in Portugal are developing carbon nanocapsules that could make radiotherapy safer and more effective for cancer patients. The experimental approach uses lithium-6 instead of traditional boron-10 in Neutron Capture Therapy.
The technique delivers targeted radiation by triggering a nuclear reaction within cancer cells, destroying them with minimal impact on surrounding healthy tissue. Lithium-6 offers higher precision and therapeutic efficiency, according to lead researcher Gil Gonçalves.
These multifunctional nanocapsules carry high concentrations of isotopes, improve delivery control, and reduce toxicity. Their natural fluorescence allows real-time monitoring inside cells.
The project involves the University of Coimbra’s Faculty of Medicine and Italy’s University of Pavia, Laboratory of Applied Nuclear Energy (LENA). Early results show strong biocompatibility and effective tumor cell accumulation.
If clinical trials confirm efficacy, the technology could lead to next-generation neutron therapy drugs. Cancer remains a leading global cause of death, with Portugal expecting a 20% rise in cases by 2040-surpassing the EU average.