Actor Eric Dane, widely recognized for his role as Dr. Mark Sloan in "Grey's Anatomy," passed away 10 months after revealing his diagnosis with amyotrophic lateral sclerosis (ALS). Dane dedicated his final months to raising funds and awareness for the rare, incurable condition, a progressive form of motor-neurone disease that leads to muscle paralysis.

Scott Garfield/Getty Images Eric Dane and Ellen Pompeo in a still from Grey's Anatomy. Both wear white medical coats over light blue and black scrubs.

"I'm trying to save my life," Dane stated in recent remarks, highlighting his commitment to "move the needle forward for myself and countless others." The 53-year-old announced his diagnosis in April 2025, describing the debilitating effects of ALS, which causes the loss of voluntary muscle control, impacting speech, eating, walking, and breathing.

He actively supported a three-year campaign launched in September to secure over $1 billion in federal funding for ALS research. Dane also joined the board of directors for Target ALS, an organization focused on developing treatments and a cure, contributing to a campaign that surpassed a $500,000 fundraising goal.

Pief Weyman/NBC via Getty Images A still of Eric Dane in Brilliant Minds. He has short grey hair and facial hair and wears a bright green jersey.

Dane also leveraged his acting career to advocate, appearing in a medical drama as a character grappling with an ALS diagnosis. He shared the challenges and catharsis of portraying a role so close to his personal experience, emphasizing the imperative to inform others about ALS and the efforts to combat it.

ALS, a progressive neurological disorder, affects individuals differently, with rapid deterioration being common. While medical advancements can improve quality of life, a cure remains elusive due to the condition's complex causes and rarity, which complicates clinical trials. Experts note that significant, sustained funding is crucial for progress in finding a cure, akin to breakthroughs seen in other complex diseases.