Melatonin, a widely used sleep aid, may carry unexpected risks. A recent analysis of over 130,000 adults indicated that those prescribed melatonin for more than a year faced an 89% higher risk of heart failure and double the mortality risk compared to non-users. While melatonin is often deemed safe for short-term use, this study suggests caution concerning long-term use.
Medical scientists point out that the safety profile of long-term melatonin is under-researched. Participants in the study were assessed based on prescription records rather than actual usage, raising questions about the control group’s composition. Experts advocate for prospective trials to clarify the safety and efficacy of melatonin as a chronic therapy.
As melatonin supplements become increasingly popular, the implications of these findings could influence how healthcare providers advise patients regarding sleep aids. Further investigation is crucial in determining the long-term effects of melatonin supplementation.